I have a soft spot for this particular collection because it contains the essay that convinced me to love David Sedaris: "All The Beauty You Will Ever Need." That and "Keeping Up" are my favorite Sedaris pieces ever; he may write that well again, but I can't imagine he (or anyone else) could get better.
Please read those, even if you don't want to read the whole book. And while you're there, catch "In The Waiting Room," a cautionary tale on the dangers of being too agreeable.
If you're listening to the audio edition of this book (which I did this time around -- I've read it several times), be sure to stick around for the credits at the end.